z-free zipdose TECHNOLOGY

the world's first 3dp dosage form.

Developed with Aprecia’s proprietary 3DP manufacturing process, ZipDose® Technology helps patients who need medicines that are easy to take and caregivers—including physicians and nurse practitioners—who want medicines that are easy to administer. By enabling delivery of high-dose medications in a rapidly disintegrating form, ZipDose overcomes patient adherence and difficulty swallowing challenges.

ENABLING NEW CAPABILITIES IN PATIENT-CENTRIC THERAPY

Using an aqueous fluid to bind together multiple layers of powder, our unique, patent-protected 3DP technology platform can be used to solve some of your toughest therapeutic challenges across multiple therapeutic areas.

HIGHER DOSE LOADS
Support dose loading up to 1,000 mg

FAST-DISSOLVING
Rapidly disintegrates on contact with liquid by breaking the bonds created during the 3DP process

taste maSking
Allows the application of enhanced taste-masking techniques

WHY ZIPDOSE?

Because of its unique digitally coded layering and zero-compression processes, ZipDose Technology can hold a high dosage load and still maintain rapid disintegration with just sip of water. ZipDose Technology can offer patients with swallowing difficulty or high pill burden an easier way to take medicine.

MARKET EXCLUSIVITY

Extend product lines and market share with broader patient reach and/or continued brand exclusivity via 505(B)(2) submissions of patent-protected ZipDose formulations.

THERAPEUTIC POSSIBILITIES

With multiple patient, manufacturing, regulatory and business benefits, ZipDose opens new opportunities in multiple therapeutic areas, bringing significant advantages to your pipeline.

MEDICAL BENEFITS

Patients and caregivers can experience a rapidly disintegrating, taste-masked, and convenient way to take or administer medicine, while providers can prescribe high-dose formulations for patients with swallowing issues or burdensome dosing regimens.

White paper
Redefining Fast Melt for Pharma
Download White paper

MEET SPRITAM, THE FIRST 3D PRINTED DRUG APPROVED BY FDA

Manufactured with Aprecia’s ZipDose 3DP technology, Spritam (levetiracetam) is available in 4 dose strengths, up to 1,000 mg, and provides appropriate patients who may have difficulty swallowing large tablets an option for an advanced fast-melt tablet. Spritam is the first 3D printed drug approved by the FDA and is currently available by prescription only.

Visit Spritam.com

LAYERS AND LAYERS OF PRECISION

Combining the precision of 3D printing and formulation science, ZipDose Technology produces rapidly disintegrating formulations of medications even at high dose loads of up to 1,000 mg.

Let's Get Started

Schedule a 3DP Discovery Assessment to learn how we can help you open new market opportunities with innovative dose forms.

Contact us at (513) 984-5000contact@aprecia.com

Try a free sample of our 3D printed ZipDose Technology ▸